St. Francis' Church, Church of St Francis, or variations on the name, may refer to:
St Francis' Church, Melbourne, Catholic church in Melbourne, Australia
São Francisco Church and Convent, Salvador, Brazil
St Francis' Church, Chester, Cheshire, Great Britain
Friary Church of St Francis and St Anthony, Crawley, West Sussex, Great Britain
St. Francis Church, Kochi, church in Cochin, Kerala, India
Templo de San Francisco de Asís, Guadalajara, Mexico
Saint Francis of Assisi Parish, Karachi, Pakistan
Franciscan Church, Zamość, Poland
Church of São Francisco (Porto), Portugal
St. Francis Chapel (Colonie, New York), United States
St. Francis of Assisi Church (Manhattan), United States